Science of IRX-2
IRX-2: a well-defined set of human cytokines
IRX-2 is a primary, cell-derived biologic with multiple active cytokine components that act on various parts of the immune system, thus addressing the need for multiple mechanisms of action to address the multiple aspects of immunosuppression in cancer.
IRX-2 is a well-defined collection of natural cytokines produced under current good manufacturing procedure(s) conditions following stimulation of human PBMCs by PHA.1 Cytokine production induced by PHA mimics that seen after brisk stimulation of human immune cells by an immunogenic pathogen or an infection. PBMC are obtained from buffy coat preparations from FDA-licensed blood banks.1
IRX-2 contains multiple human cytokines that promote or enhance an immune response. The composition of these cytokines is reproducible and extensively monitored.1